Eyal Grunebaum Selected Research

Pulmonary Alveolar Proteinosis

5/2014	Pulmonary alveolar proteinosis in adenosine deaminase-deficient mice.
12/2013	Recent advances in understanding and managing adenosine deaminase and purine nucleoside phosphorylase deficiencies.

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Eyal Grunebaum Research Topics

Disease

21	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2023 - 03/2004
12	Purine Nucleoside Phosphorylase Deficiency 01/2022 - 03/2004
11	Severe combined immunodeficiency due to adenosine deaminase deficiency 01/2023 - 07/2007
8	Graft vs Host Disease (Graft-Versus-Host Disease) 03/2024 - 02/2008
8	Infections 12/2023 - 10/2004
4	Chronic Granulomatous Disease 01/2024 - 01/2017
4	Hypersensitivity (Allergy) 01/2020 - 03/2004
3	Neoplasms (Cancer) 01/2022 - 06/2011
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 03/2024 - 01/2024
2	Inflammation (Inflammations) 03/2024 - 11/2022
2	Liver Diseases (Liver Disease) 12/2023 - 10/2009
2	Anaphylaxis (Anaphylactic Shock) 01/2022 - 01/2022
2	Agammaglobulinemia (Hypogammaglobulinemia) 11/2021 - 01/2020
2	Lymphopenia (Lymphocytopenia) 01/2021 - 10/2004
2	Primary Immunodeficiency Diseases 01/2019 - 02/2008
2	Pulmonary Alveolar Proteinosis 05/2014 - 12/2013
2	Ataxia (Dyssynergia) 12/2013 - 03/2004
1	WHIM syndrome 11/2022
1	Milk Hypersensitivity (Milk Allergy) 01/2022
1	Colitis 11/2021
1	COVID-19 11/2021
1	Bacteremia 01/2021
1	Otitis Media 01/2021
1	Pneumonia (Pneumonitis) 01/2021
1	Cytopenia 01/2020
1	Autoimmune Lymphoproliferative Syndrome 01/2019
1	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 01/2019
1	Common Variable Immunodeficiency 01/2019
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2018
1	Bone Marrow Failure Disorders 01/2018
1	Nijmegen Breakage Syndrome 01/2018
1	Epstein-Barr Virus Infections 01/2018
1	Autoimmune Diseases (Autoimmune Disease) 01/2018
1	Type 1 Hyper-IgM Immunodeficiency Syndrome 04/2017
1	Wiskott-Aldrich Syndrome 01/2017
1	X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency) 01/2017
1	Hematologic Neoplasms (Hematological Malignancy) 01/2017
1	Metabolic Diseases (Metabolic Disease) 01/2016
1	Multiple Myeloma 01/2016
1	Body Weight (Weight, Body) 08/2015
1	Overweight 08/2015
1	Inborn Genetic Diseases (Disease, Hereditary) 05/2013
1	ZAP70 deficiency 04/2013

Drug/Important Bio-Agent (IBA)

13	Adenosine DeaminaseIBA 01/2023 - 07/2007
10	EnzymesIBA 01/2022 - 03/2004
8	Purine-Nucleoside PhosphorylaseIBA 11/2018 - 03/2004
7	purineIBA 01/2021 - 12/2008
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2006
4	SteroidsIBA 01/2024 - 02/2010
2	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2023 - 02/2008
2	Oxidoreductases (Dehydrogenase)IBA 12/2023 - 12/2023
2	Biomarkers (Surrogate Marker)IBA 11/2022 - 01/2022
2	Platelet Activating FactorIBA 11/2022 - 01/2022
2	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2022 - 01/2021
2	trichostatin A (A 300)IBA 01/2022 - 01/2021
2	Niacinamide (Nicotinamide)FDA LinkGeneric 01/2022 - 01/2021
2	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 01/2022 - 01/2021
2	Tacrolimus (Prograf)FDA LinkGeneric 01/2020 - 04/2009
2	Calcineurin InhibitorsIBA 01/2020 - 04/2009
2	CD40 Ligand (CD40L)IBA 01/2019 - 07/2012
2	DNA Ligase ATPIBA 01/2018 - 12/2008
2	Surface-Active Agents (Surfactants)IBA 12/2013 - 06/2012
2	pegademase bovine (pegADA)FDA Link 10/2009 - 07/2007
2	Uric Acid (Urate)IBA 12/2008 - 10/2004
1	vedolizumabIBA 03/2024
1	neutrophil cytosolic factor 1IBA 01/2024
1	NADP (NADPH)IBA 12/2023
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2023
1	elapegademaseIBA 01/2023
1	CXC ChemokinesIBA 11/2022
1	1-Alkyl-2-acetylglycerophosphocholine Esterase (PAF Acetylhydrolase)IBA 01/2022
1	Immunoglobulin E (IgE)IBA 01/2022
1	pifithrinIBA 01/2022
1	fludarabineIBA 01/2022
1	CTLA-4 AntigenIBA 11/2021
1	LipopolysaccharidesIBA 11/2021
1	SARS-CoV-2 spike proteinIBA 11/2021
1	Amoxicillin (Wymox)FDA LinkGeneric 01/2021
1	Methylcellulose (BFL)IBA 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2020
1	Immunoglobulins (Immunoglobulin)IBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2018
1	EpitopesIBA 01/2016
1	Busulfan (Busulfex)FDA Link 08/2015
1	Antigen-Antibody Complex (Immune Complex)IBA 12/2013
1	kappa Opioid Receptors (kappa Opioid Receptor)IBA 05/2013
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 05/2013
1	MitogensIBA 07/2012
1	Interleukin-2 Receptors (IL 2 Receptor)IBA 07/2012

Therapy/Procedure

8	Transplantation 03/2024 - 06/2012
6	Bone Marrow Transplantation (Transplantation, Bone Marrow) 02/2011 - 02/2006
4	Hematopoietic Stem Cell Transplantation 03/2024 - 02/2008
4	Therapeutics 12/2023 - 04/2009
3	Cell Transplantation 01/2024 - 10/2012
2	Liver Transplantation 01/2020 - 01/2019
1	Immunomodulation 03/2024
1	Enzyme Replacement Therapy 01/2023
1	Organ Transplantation 01/2018
1	Stem Cell Transplantation 12/2013
1	Emergency Treatment 04/2013